Sodium hydrogen carbonate 8.4%, 10X20 ml

Sodium bicarbonate solution 8.4% Köhler, solution for infusion

Sodium hydrogen carbonate solution 8.4% Köhler is a corrective electrolyte solution that is used to treat acidosis.The solution is used to treat metabolic acidosis, as well as alkalinization in barbiturate and salicylate poisoning.No prescription is required for this product.

Areas of application

The 8.4% Köhler sodium hydrogen carbonate solution is used for metabolic acidosis and for alkalinization in barbiturate and salicylate poisoning.

Contraindications

The solution must not be used in cases of alkalosis, hypernatremia and hypokalemia.It should not be used together with solutions containing calcium and magnesium or mixed with solutions containing phosphates.

Dosage instructions

Unless otherwise prescribed, the solution should be administered as a continuous drip up to a maximum of 25 drops per minute and 100 ml per day, taking the acid-base balance into account.The dosage can be calculated using the following formula: ml sodium bicarbonate solution 8.4% = bicarbonate deficit (mEq/l x kg body weight x 0.3).The solution can be infused undiluted or diluted with glucose solution 5% in the same volume ratio.

Type of application

Köhler's sodium bicarbonate solution 8.4% is used for intravenous infusion.

Side effects

If the contraindications and instructions are followed, there are no known side effects.

Notes

Paravenous application can result in necrosis.Controls of the acid-base balance and the serum ionogram are required.Caution is advised in the event of hypokalemia.If the dose is exceeded, there is a risk of hypocalcemic tetany.

Type of storage

The solution should be protected from light and not stored above 25°C.After the expiry date, the medicine should no longer be used.Medicines should be kept out of the reach of children.

Composition

Medicinally active ingredient: 20 ml of infusion solution contains 1.68 g of sodium hydrogen carbonate.Other ingredients: edetic acid, disodium salt, 2 H20, water for injections.

Dosage form and pack sizes

Ampoules of 20 ml in packs of 1 x 5 ampoules, 1 x 10 ampoules, 1 x 25 ampoules, 50 (2 x 25) ampoules and 100 (4 x 25) ampoules.

Note on dilution

Sodium bicarbonate solution 8.4% Köhler can be diluted and infused in the same volume ratio or with a larger volume, such as 50 ml, 100 ml or 250 ml, of an isotonic saline solution (NaCl 0.9%).

Pharmaceutical entrepreneur and manufacturer

Dr.Franz Köhler Chemie GmbH, Werner-von-Siemens-Str.14-28, 64625 Bensheim.

Co-distributor

Köhler Pharma GmbH, Neue Bergstraße 3-7, 64665 Alsbach-Hähnlein.

Final revision

This leaflet was last revised in February 2016.