Isotonic saline solution 0.9% PE-infusion solution, 10X500 ml

Isotonic saline solution 0.9% Bernburg

The isotonic saline solution 0.9% Bernburg is an electrolyte solution used for intravenous infusion.It is used for fluid and electrolyte replacement in various conditions such as hypochloremic alkalosis, chloride losses, short-term intravascular volume replacement and hypotonic and isotonic dehydration.

Areas of application

This solution is used for:

Fluid and electrolyte replacement in hypochloremic alkalosis, chloride losses, short-term intravascular volume replacement, hypotonic dehydration and isotonic dehydration.

Contraindications

The application is not suitable for overwatering conditions (hyperhydration conditions).

Precautions for use

Particular caution should be exercised in cases of decreased blood potassium (hypokalemia), increased blood sodium (hypernatremia), increased blood chloride (hyperchloremia), and conditions requiring restrictive sodium intake, such as heart failure, generalized edema, pulmonary edema, hypertension, eclampsia, and severe renal insufficiency.

Pregnancy and breastfeeding

There are no concerns about use during pregnancy and breastfeeding.

Interactions with other medicines

So far no interactions are known.

Warnings

Electrolyte and fluid status checks are required.

Dosage

The dosage depends on the fluid and electrolyte requirements, which are usually 40 ml/kg body mass/day or 2 mmol sodium/kg body mass/day.The maximum daily dose is 3-6 mmol sodium/kg body mass for adults and 3-5 mmol sodium/kg body mass for children.The infusion rate depends on the clinical situation.

Type of application

The solution is used for intravenous infusion.

Advice in case of overdose

Symptoms of overdose may include overhydration, increased sodium and chloride levels in the blood (hypernatremia, hyperchloremia), hyperosmolarity and an acidotic metabolic state.In the event of an overdose, the supply of the solution should be interrupted, accelerated elimination via the kidneys should be promoted and the supply of the corresponding electrolytes should be reduced.

Side effects

Possible side effects include increased sodium and chloride levels in the blood (hypernatremia, hyperchloremia).

Notes and information on shelf life

Use only clear solutions in intact containers.The solution must no longer be used after the expiry date.Medicines should be kept out of the reach of children.

Qualitative and quantitative composition

1000 ml infusion solution contains 9.0 g sodium chloride (corresponds to mmol/l: Na+ 154, Cl- 154).Other ingredients are water for injections, sterile and pyrogen-free.The pH value is between 4.5 and 7.0, the theoretical osmolarity is 309 m0sm/l and the titration acidity up to pH 7.4 is <0.1 mmol/l.

Dosage form and contents

The infusion solution is available in different pack sizes, including 10 x 100 ml, 1 x 250 ml, 10 x 250 ml, 1 x 500 ml, 10 x 500 ml, 1 x 1000 ml and 10 x 1000 ml. Not all pack sizes may be marketed.

Pharmaceutical entrepreneur and manufacturer

Serumwerk Bernburg AG, Hallesche Landstraße 105 b, 06406 Bernburg (Saale).

No prescription is required for this product.