Isotonic saline solution 0.9% Bernburg infusion solution, 250 ml

Isotonic saline solution 0.9% Bernburg

The isotonic saline solution 0.9% Bernburg is an electrolyte solution used for intravenous infusion.The active ingredient in this solution is sodium chloride.It is used for fluid and electrolyte replacement in various conditions such as hypochloremic alkalosis, chloride losses, short-term intravascular volume replacement and hypotonic and isotonic dehydration.No prescription is required for this product.

Areas of application

The isotonic saline solution 0.9% Bernburg is used for fluid and electrolyte replacement in hypochloremic alkalosis, chloride losses, short-term intravascular volume replacement, hypotonic dehydration and isotonic dehydration.

Contraindications

The solution must not be used in overwatering conditions (hyperhydration conditions).

Precautions for use

Particular caution is required in the case of reduced potassium content in the blood (hypokalemia), increased sodium content in the blood (hypernatremia), increased chloride content in the blood (hyperchloremia) and diseases that require restrictive sodium intake, such as heart failure, generalized edema, pulmonary edema, high blood pressure, eclampsia and severe renal insufficiency.

Pregnancy and breastfeeding

There are no concerns about use during pregnancy and breastfeeding.

Interactions with other medicines

So far no interactions are known.

Warnings

Electrolyte and fluid status checks are required.

Dosage

The dosage usually depends on the fluid and electrolyte requirements, which in adults are around 40 ml/kg body mass/day or 2 mmol sodium/kg body mass/day.The maximum daily dose is determined by fluid and electrolyte requirements.For adults a value of 3-6 mmol sodium/kg body mass applies, for children it is 3-5 mmol sodium/kg body mass.In the case of hypertonic dehydration, an infusion rate that is too fast should be avoided at all costs.

Type of application

The solution is used for intravenous infusion.

Advice in case of overdose

Symptoms of overdose may include overhydration, increased sodium and chloride content of the blood (hypernatremia, hyperchloremia), hyperosmolarity and induction of an acidotic metabolic state.In the event of an overdose, the supply of the solution must be interrupted, accelerated elimination via the kidneys and the supply of the corresponding electrolytes reduced.

Side effects

Possible side effects include increased sodium and chloride levels in the blood (hypernatremia, hyperchloremia).

Notes and information on shelf life

Use only clear solutions in intact containers.The isotonic saline solution 0.9% Bernburg may no longer be used after the expiry date.Medicines should be kept out of the reach of children.

Qualitative and quantitative composition

1000 ml infusion solution contains: Active ingredient: sodium chloride 9.0 g (=mmol/l: Na+ 154, CI- 154).Other ingredients: Water for injections.Sterile and pyrogen-free.pH: 4.5-7.0.Theoretical osmolarity: 309 m0sm/l.Titration acidity up to pH 7.4: <0.1 mmol/l.

Dosage form and contents

The infusion solution is available in different pack sizes, including 10 x 100 ml, 1 x 250 ml, 10 x 250 ml, 1 x 500 ml, 10 x 500 ml, 1 x 1000 ml and 10 x 1000 ml. Not all pack sizes may be marketed.

Further information

Use bag unventilated.For technical reasons, the polyethylene vial contains a residual volume of air.Pressure infusions with the plastic infusion bottle may only be carried out under controlled conditions, otherwise there is a risk of an air embolism.

Pharmaceutical entrepreneur and manufacturer

Serumwerk Bernburg AG, Hallesche Landstraße 105 b, 06406 Bernburg.