Lophakomp Procaine 2 ml solution for injection, 50X2 ml

Lophakomp®-Procaine 2 ml

Solution for injection for use in adolescents over 15 years and adults.No prescription is required for this product.

Lophakomp®-Procaine 2 ml is a medicine for local anesthesia (local anesthetic of the ester type).It is used within the framework of neural therapeutic application principles.

Application

Lophakomp®-Procaine 2 ml should only be injected by people with the appropriate knowledge to successfully carry out the respective application.Lophakomp®-Procaine 2 ml is generally used by a doctor.

Lophakomp®-Procaine 2 ml is injected into healthy skin (intracutaneously).The dosage must be taken individually depending on the specifics of the individual case and will be determined by your doctor.

Area of application

Lophakomp®-Procaine 2 ml is indicated for intracutaneous application into healthy skin, such as:B. for specific local application within the framework of neural therapeutic application principles.

Active ingredients / ingredients / ingredients

1 ml injection solution contains 20 mg procaine hydrochloride (corresponding to 40 mg procaine hydrochloride per ampoule).The other ingredients are sodium edetate (Ph. Eur.), sodium chloride, hydrochloric acid 3.6%, water for injections.

Contraindications

Lophakomp®-Procaine 2 ml must not be used if you are allergic to procaine, other ester-type local anesthetics, sulfonamides (certain group of antibiotics), benzoic acid (parabens) or any of the other ingredients of this medicine.

Lophakomp®-Procaine 2 ml must not be used if there is a known deficiency of a certain endogenous substance (pseudocholinesterase) which results in a significantly slower breakdown of procaine.

Lophakomp®-Procaine 2 ml must not be used for injection into arteries, into the area surrounding the outer covering of the central nervous system (epidural) or into the spinal canal (spinal).

Dosage

Always use the medicine exactly as directed.Please ask your doctor or pharmacist if you are not sure.

The medicine is generally used by a doctor.Please ask your doctor if you are unsure about how to use it.

The basic rule is that only the smallest dose that achieves the desired sufficient nerve block may be administered.The dosage must be determined individually according to the specifics of the individual case.

Unless specified otherwise by the doctor, the usual dose for individual types of application for adolescents over 15 years of age and adults of average height is: skin wheals per wheal up to 10 mg corresponding to 0.5 ml injection solution.

The recommended maximum dose for a single dose in tissues from which drugs are rapidly absorbed is 500 mg procaine (corresponding to 25 ml injection solution).When used in the head, neck and genital area, the recommended single-time maximum dose is 200 mg procaine (within 2 hours).

In patients with certain previous illnesses (vascular occlusions, hardening and narrowing of the vessels (arteriosclerosis) or nerve damage due to diabetes), the dose should also be reduced by a third.If liver or kidney function is impaired, increased plasma levels may occur, especially with repeated use.In these cases, a lower dose range is also recommended.

Please talk to your doctor if you think the effect is too strong or too weak.

The duration of application is in principle not limited, but please note the information under areas of application.

If you have used more than you should, your doctor must be informed immediately.Symptoms of an overdose may include restlessness, dizziness, auditory and visual disturbances as well as tingling, especially in the tongue and lip area, slurred speech, chills and muscle twitching.As the poisoning of the central nervous system progresses, there is increasing dysfunction of the brainstem with the symptoms of respiratory restriction and coma and even death.

Emergency measures and antidotes will be initiated immediately by the attending physician based on the symptoms of the disease.

Do not use a double dose if you forget the previous dose.

The treatment can be stopped at any time.

Intake

The medicine is injected into the skin (intracutaneously).

It should only be injected by people with the appropriate knowledge to carry out the respective application successfully.

As a general rule, only low-concentration solutions of procaine should be used for continuous use.

Repeated use of this medicine can lead to reversible loss of effect due to tachyphylaxis (rapid development of tolerance to the medicine).

The injection solution is only intended for one-time use.The application must take place immediately after opening the container.Any unused leftovers must be discarded.

Patient information

Particular caution is required when using Lophakomp®-Procaine 2 ml if you suffer from a certain form of muscle weakness (myasthenia gravis), a disorder of the cardiac conduction system or a weakness of the heart muscle, or if the injection is to be carried out into an inflamed area.

Before use, the treating doctor will always ensure that the circulatory system is well filled, carry out careful circulatory monitoring and have all measures available for ventilation, treatment of seizures and resuscitation.

The doctor must also find out from you whether you have had an allergic reaction to other drugs that are chemically related to procaine, as an allergic reaction to procaine can then also occur (paragroup allergy).This can e.g.B. sulfonamides (certain group of antibiotics), oral antidiabetics (medicines for diabetes), certain dyes, X-ray film developers or other local anesthetics.

If procaine can only be broken down extremely slowly because a certain body substance is not as active (pseudocholinesterase deficiency), side effects from procaine are more likely to occur.

When used in the neck and head area, there is a higher degree of danger because the risk of symptoms of poisoning in the central nervous system is increased.

To avoid side effects, the following points should be taken into account: In certain cases, apply an additional drip before use, select the dosage as low as possible, generally do not use a vasoconstrictor additive, carefully suck in two levels before injection (rotation of the cannula), be careful when injecting into infected areas (due to increased absorption with reduced effectiveness), inject slowly, check blood pressure, pulse and pupil size.

It should be noted that during treatment with anticoagulants (anticoagulants, such as heparin), non-steroidal anti-inflammatory drugs or plasma substitutes, not only can accidental vascular injury as part of pain treatment lead to serious bleeding, but that in general an increased tendency to bleeding must be expected.Therefore, have appropriate laboratory tests carried out before use.If necessary, the anticoagulant treatment should be discontinued as soon as possible.

Use with simultaneous preventive therapy to avoid thrombosis with low molecular weight heparin should only be carried out with particular caution.

There is no experience with use in children and adolescents under 15 years of age from which general dosage recommendations can be derived.

In older people, a dosage adjustment is recommended according to the respective general condition.

Let your doctor decide on a case-by-case basis whether you can actively participate in traffic, operate machines or carry out work without secure support.

Pregnancy

Only use this medicine during pregnancy if your doctor thinks it is absolutely necessary.

Procaine hydrochloride passes into breast milk.However, for short-term use, interruption of breastfeeding will not be necessary.If repeated treatment or treatment with higher doses is necessary, you should stop breast-feeding.

Notes

Lophakomp®-Procaine 2 ml contains sodium, but less than 1 mmol (23 mg) per ampoule, i.e. it is almost “sodium-free”.Please do not use this medicine after the expiry date stated on the pack or outer packaging.The expiry date refers to the last day of the specified month.