CC Nefro film-coated tablets, 200 pcs

Area of application

The drug serves as a phosphate binder and is used for elevated serum phosphate (hyperphosphatemia) in chronic kidney failure, especially in patients on dialysis treatment.No prescription is required for this product.

Active ingredients and ingredients

The active ingredient of this medicine is calcium carbonate, with each film-coated tablet containing 500 mg calcium carbonate and 200 mg calcium.In addition, the preparation contains the following excipients: microcrystalline cellulose, crospovidone, hypromellose, lactose-1-water, macrogol 6000, magnesium stearate (vegetable), polyoxyethylene (8) monostearate, povidone K30, colloidal silicon dioxide, talc and titanium dioxide.

Contraindications

This medicine must not be taken if you are allergic to calcium carbonate or any of the other ingredients of this medicine.The preparation should also not be used if calcium concentrations in the blood are too high (hypercalcemia), low serum phosphate (hypophosphatemia), kidney stones containing calcium or if there is a lack of free hydrochloric acid in the gastric juice.

Dosage

The dosage depends on the serum phosphate level and should be done in consultation with the treating doctor.Adults can generally take 1 to 3 tablets three times a day, although the maximum dose of 7 tablets (corresponding to 1400 mg calcium) should not be exceeded.There are insufficient data for children and adolescents under 18 years of age, so use is not recommended for this age group.

The therapy is long-term therapy and requires regular medical monitoring.Overdose may result in a high concentration of calcium in the blood (hypercalcemia), which may include symptoms such as muscle weakness, abdominal pain, constipation, nausea, vomiting, intense thirst, irregular heartbeat and loss of consciousness.In the event of an accidental overdose, a doctor should be consulted immediately.

If you forget to take a dose, you should not take twice as much.It must not be taken after a meal and should not be interrupted or stopped without consulting your doctor.

Intake

The film-coated tablets should be taken whole with a little liquid immediately before or with meals.

Patient information

Particular caution is required in the case of impaired kidney function, kidney stones, kidney calcification, increased calcium excretion in the urine and reduced phosphate concentration in the blood.If additional calcium or alkalis are taken with food or other medicines, the calcium level in the blood and urine should be monitored.Drinking plenty of fluids can reduce the risk of kidney stones forming.Therapy requires regular monitoring of serum calcium and serum phosphate levels.

No studies have been conducted on the effects on the ability to drive and use machines.

Pregnancy

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.There have been no reports of harmful effects of calcium during pregnancy and breastfeeding in humans.During pregnancy, serum calcium levels must be well controlled because prolonged hypercalcemia can lead to physical malformation and mental retardation of the child.

Notes

For information about risks and side effects, read the package leaflet and ask your doctor or pharmacy.

Other

The active ingredient calcium carbonate is converted into soluble calcium chloride in the stomach and is thus bioavailable.In achlorhydria, solubility can be impaired and bioavailability reduced.However, bioavailability is largely guaranteed if the medicine is taken with food.

If there is a family history of calcium-containing kidney stones, absorptive hypercalciuria should be ruled out.

Treatment with the drug requires regular monitoring of serum calcium and serum phosphate levels.The calcium phosphate product should under no circumstances exceed 5.3 mmol per liter, in which case treatment should be discontinued.

If long-term treatment with the drug is necessary in the case of chronic reduced kidney function, the serum phosphate and serum calcium levels must be checked, especially if vitamin D preparations are taken at the same time.